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Examples of high-resolution UHPLC and the use of generic gradient methodologies in drug development from Michael's publications...
Flexibility of UHPLC

Flexibility of UHPLC

from fast analysis with good resolution to very high-resolution separation.

High-resolution UHPLC

High-resolution UHPLC

separation of drug product with 4 APIs

High-resolution separation by UHPLC

High-resolution separation by UHPLC

Retention marker solution and tox lot chromatograms

2-min and 5-min generic methods

2-min and 5-min generic methods

separation of mixture of NCEs using generic UHPLC methodologies

2-min generic LC/MS method

2-min generic LC/MS method

Separation of 12 NCEs

Generic 10-min HPLC method

Generic 10-min HPLC method

Cleaning verification method using LC/UV

Comparison of fast UHPLC

Comparison of fast UHPLC

fully porous vs. SPP

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